Saturday, May 26, 2018

The etiology and clinical symptom of rhinitis

The etiology and clinical symptom of rhinitis



1. Virus infection Viral infection is the primary cause or secondary bacterial infection on the basis of viral infection. It is known that more than 100 kinds of viruses can cause this disease, the most common is the nasal virus, followed by influenza and deputy influenza virus, adenovirus, coronavirus, Coxsackie virus and mucus and vice-mucus virus.

The virus is transmitted mainly through the respiratory tract, followed by contamination or food into the body.

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2. Genetic factors A family history of allergic reactions is susceptible to this disease. Patients with family members have asthma, urticaria or drug allergy history. In the past, this patient was a special individual, and its ability to produce IgE antibodies in vivo was higher than that of normal people.

But in recent years, it has been found that there is no significant difference in the incidence of twins and the general population.

3. Nasal mucosa susceptibility Susceptibility arises from the constant stimulation of the antigen substance, but its susceptibility to the mast cells in the nasal mucosa, the number of neutrophils and the ability to release the chemical medium.

It has been proved that the number of nasal mucosa in patients with allergic rhinitis is not only higher than normal, but also has a strong ability to release chemical media.

4. Antigen substances An antigen substance that stimulates the body to produce an IgE antibody is called a allergen. The allergen enters the nasal mucosa again, and then binds to the corresponding IgE and causes allergic reactions.


Causes the disease the allergen according to it enters the human body the way divides into the inhalation sex and the food sex two main categories.

(1)
Inhaled allergen

① pollen is not all plant pollen can cause disease, only those who have a large amount of pollen, vegetation area wide, allergens strong, and the use of wind to spread pollen is most likely to become allergens. Because of the difference of vegetation varieties, the pollen with allergen in different regions is also different.

② fungi are widely distributed in nature, mainly in soil and corrupt organic matter. Both hyphae and spores have the allergen, but the spore is stronger.

③ House Dust mite is an arthropod portal spider. The adult size is generally 300~500μm. Main parasitic hos indoor every corner, in which mattress, pillow, sofa mat and other places in the dust most. The excretion of mites, the eggs, the cuttings and the limbs of their fragments can become allergens.

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④ Animal dander is one of the strongest allergens. Susceptible individuals may be sensitized if they are in contact with the animals concerned for a long time. The nasal symptoms can also be stimulated by contact with even a small amount of dander after sensitization.

⑤ indoor dust is one of the common allergens causing perennial rhinitis.

(2) The allergen should refer to the allergens of the nasal symptoms caused by the digestive tract entering the body. Its role in the nasal mucosa is very complex, so far it is still unclear.

Milk, eggs, fish and shrimp, meat, fruit, and even some kind of vegetable can become allergens.

Clinical Symptoms

1. Symptoms

(1) Nasal congestion is characterized by intermittent. Nasal congestion during daytime, hot weather, labor or exercise is reduced and nasal congestion increases during nighttime, sit-ins or cold. Another characteristic of nasal congestion is the alternating sex. If lying on the side, the lower nasal cavity obstruction, the upper side nasal ventilation good.

As a result of nasal congestion, sometimes have a sense of loss of smell, headache, dizziness, speech is a closed nasal symptoms.

(2) Many tears often for mucus or sticky purulent sex, occasionally into purulent.

More purulent than after secondary infection occurs.

(3) Olfactory decline is caused by more than two kinds of reasons, one is swollen nasal mucosa, nasal congestion, airflow can not enter the olfactory region, two for the olfactory region mucosa by chronic inflammation long-term stimulation, olfactory function decreases or disappears.

(4) Headache, dizziness, chronic sinusitis more than the head heavy feeling.

(5) The general performance of most people also have headaches, loss of appetite, easy fatigue, memory loss and insomnia.

2. Types of rhinitis

Rhinitis symptom has many kinds, according to the type of rhinitis is different, rhinitis symptom is also different:

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(1) Chronic rhinitis long-term intermittent or alternating nasal congestion, resulting in dizziness and brain swelling, seriously affecting sleep, work and learning.

Sticky purulent nose often pours into pharynx cavity, appear cough, phlegm. (2) Acute rhinitis

① early 1-2 days. Patients often have systemic discomfort, chills, fever, anorexia, headache and so on. Nasal cavity and nasopharynx dry, burning sensation, nasal itching, frequent sneeze.

② Acute period 2-5 days. The original symptom is aggravating.

Adult temperature of 38 degrees, children up to 39 degrees, often because of high fever vomiting, diarrhea, coma and even convulsions.

(3) Drug-induced rhinitis long-term use of a variety of nasal mucosa injury rhinitis drugs or laser, surgery, leading to persistent nasal congestion, often bleeding.

(4) atrophic rhinitis breath odor, nasal secretions are massive, tubular-like pus scab, not easy to blow out, pulling out the dry scab, a small number of epistaxis.

Often mistaken for a cold early rhinitis.


After cooler weather, some patients in the morning after the continuous sneezing, runny nose, temperature difference when the nasal congestion, mistakenly thought it was a cold and casually eat some cold medicine, resulting in worsening illness.

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