Clinical significance of CA125 of popular science carbohydrate antigen
Carbohydrate antigen CA125 is a common hormone type in the human body, and also the most studied ovarian cancer marker.
At the same time, it has a certain positive rate for epithelial ovarian cancer, cervical cancer, uterine cancer, endometrial carcinoma, pancreatic cancer, lung cancer, gastric cancer, colorectal cancer and breast carcinoma.
Benign gynecological diseases (pelvic inflammatory disease, ovarian cysts, etc.) and early pregnancy can also occur in different levels of serum CA125 content increased.
The positive critical value of serum CA125 (RIA) in normal subjects was: male >35ku/l or 35u/ml, female >40μg/l positive. 。
It is often used to diagnose ovarian cancer and to determine whether there is recurrence after surgery. The clinical significance of serum CA125 level in ① ovarian cancer patients was significantly elevated, and the CA125 level of operative and chemotherapy-effective persons decreased rapidly.
If there is a recurrence, the CA125 may precede the clinical symptoms.
② Other non-ovarian malignancies also have a certain positive rate, such as breast cancer 40%, pancreatic cancer 50%, gastric cancer 47%, lung cancer 44%, colon cancer 32%, other gynecological tumors 43%.
③, such as endometriosis, pelvic inflammatory disease, ovarian cyst, pancreatitis, hepatitis, liver cirrhosis, etc., although there are different degrees of increase, the positive rate is low.
④ was found to have elevated CA125 in pleural and ascites, and higher concentrations of CA125 were detected in amniotic fluid. ⑤ in the first 3 months of early pregnancy, there is also the possibility of CA125 elevation.
Carbohydrate antigen CA125 is a common hormone type in the human body, and also the most studied ovarian cancer marker.
At the same time, it has a certain positive rate for epithelial ovarian cancer, cervical cancer, uterine cancer, endometrial carcinoma, pancreatic cancer, lung cancer, gastric cancer, colorectal cancer and breast carcinoma.
Benign gynecological diseases (pelvic inflammatory disease, ovarian cysts, etc.) and early pregnancy can also occur in different levels of serum CA125 content increased.
The positive critical value of serum CA125 (RIA) in normal subjects was: male >35ku/l or 35u/ml, female >40μg/l positive. 。
It is often used to diagnose ovarian cancer and to determine whether there is recurrence after surgery. The clinical significance of serum CA125 level in ① ovarian cancer patients was significantly elevated, and the CA125 level of operative and chemotherapy-effective persons decreased rapidly.
If there is a recurrence, the CA125 may precede the clinical symptoms.
② Other non-ovarian malignancies also have a certain positive rate, such as breast cancer 40%, pancreatic cancer 50%, gastric cancer 47%, lung cancer 44%, colon cancer 32%, other gynecological tumors 43%.
③, such as endometriosis, pelvic inflammatory disease, ovarian cyst, pancreatitis, hepatitis, liver cirrhosis, etc., although there are different degrees of increase, the positive rate is low.
④ was found to have elevated CA125 in pleural and ascites, and higher concentrations of CA125 were detected in amniotic fluid. ⑤ in the first 3 months of early pregnancy, there is also the possibility of CA125 elevation.
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